Season 2 (2005)
Episodes
- 1. Neil Patrick Harris / Karen Fisher / Nickel Creek
- 2. Bruce Campbell / Melinda Clarke / Flight of the Conchords
- 3. Patricia Arquette / Connie Schultz / Paul Weller
- 4. Carla Gugino / Alice Cooper
- 5. Alyson Hannigan / Steve Jones
- 6. Cybill Shepherd / Phil Keoghan / Institute
- 7. Tyra Banks / Tyler James Williams / Ted Alexandro
- 8. Nick Cannon / Jeff Probst / Lawrence Turman
- 9. Aisha Tyler / Seth MacFarlane / Thirty Seconds to Mars
- 10. Susan Sarandon / Tom Everett Scott / INXS
- 11. Danny Bonaduce / Diane Farr / Shaggy
- 12. Maria Bello / Jason Segel
- 13. Alan Alda / Jennifer Coolidge
- 14. Fran Drescher / Robert David Hall / Jo Dee Messina
- 15. Toni Collette / Dave Price / Robert Plant & Strange Sensation
- 16. Julian McMahon / Jennifer Finnigan
- 17. Taryn Manning / Dr. Drew / Butch Bradley
- 18. David Duchovny / Sinéad O'Connor
- 19. Henry Winkler / Aron Ralston / Julie Gribble
- 20. Illeana Douglas / Macy Gray
- 21. Macy Gray / Nuala O'Faolain / Rihanna
- 22. Dennis Hopper / Cheryl Hines / Sarge
- 23. Joe Mantegna / Sue Johanson
- 24. Sanjay Gupta / Stephen Collins
- 25. Bill Nye / Kevin Bacon & Michael Bacon / Bacon Brothers
- 26. Joely Fisher / McG / Switchfoot
- 27. Melina Kanakaredes / Stephen Robinson
- 28. Betty White / Rhona Mitra / Ray J
- 29. Stockard Channing / Michael Connelly / Jamie Cullum
- 30. Jason Schwartzman / Mitch Braswell / Paul Weller
- 31. Sharon Osbourne
- 32. Maria Bartiromo / Jamie Kaler / Clint Black
- 33. Anthony LaPaglia / Jeri Ryan
- 34. Charlie Sheen / Marissa Jaret Winokur / Franz Ferdinand
- 35. Gina Gershon / Rob Zombie / Sinéad O'Connor
- 36. Hugh Laurie / Twiggy / Patty Loveless
- 37. Brenda Blethyn / Jim Sheridan / John Roy
- 38. John Leguizamo / Kara Cooney / My Morning Jacket
- 39. John Malkovich
- 40. Xzibit / Doug Savant / Buddy Guy
- 41. James Belushi / Parminder Nagra / Matisyahu
- 42. Patti Smith / John Lahr
- 43. Anne Heche / Tom Amandes / Jay Larson
- 44. RZA / Josh Schwartz / Amos Lee
- 45. Jon Favreau / Randy Cohen / Maz Jobrani
- 46. Juliette Lewis / Brian Van Holt
- 47. Jerry O'Connell / Joely Richardson / The Fray
- 48. Regis Philbin / Maureen Dowd
- 49. Jennifer Love Hewitt / James Denton / Robert Plant
- 50. Danny Bonaduce / Paul Haggis
- 51. Ted Danson / Kristen Bell / Matt Fulchiron
- 52. Sela Ward / Lawrence O'Donnell / Chris Botti / Paul Buchanan
- 53. Tony Shalhoub / Mitch Albom
- 54. Miranda Lambert / Malachy McCourt
- 55. Tom Arnold / Helen Fielding / Lifehouse
- 56. Jon Cryer / Amy Yasbeck
- 57. John Waters / David Steinberg / Nada Surf
- 58. Poppy Montgomery / Mancow
- 59. Michelle Yeoh / Jeremy Roenick / Trey Anastasio
- 60. Chris Isaak / Sara Gilbert / Keaton Simons
- 61. Dennis Quaid / Bill Nye / Bob Marley
- 62. Dwight Yoakam / Teri Garr
- 63. Little Richard / Brian Cox
- 64. Téa Leoni / Amy Tan / RZA
- 65. Katey Sagal / Colin Hanks / Brian McKnight
- 66. Drew Pinsky / Bob Spitz
- 67. Fred Willard / Connie Schultz
- 68. Rob Morrow / Bob Marley
- 69. Don Rickles / Ivana Miličević / Aimee Mann
- 70. Daryl Hannah / Thomas Lennon
- 71. Cheryl Hines / Derek Luke / Trey Anastasio
- 72. Phil McGraw / Sebastian Maniscalco
- 73. Seth Green / Peter Bart / Peter Guber
- 74. Tom Selleck / Connie Britton / Ian Edwards
- 75. Steven Wright / Lola Glaudini / Anthony Hamilton
- 76. Allison Janney / John C. McGinley / The 88
- 77. Greg Kinnear / Paula Poundstone / Ming Tsai
- 78. Thomas Cavanagh
- 79. Vanessa Williams / Rogue Wave
- 80. Mimi Rogers / Living Things
- 81. Drew Pinsky / Amy Yasbeck / Wicked Tinkers
- 82. Jim Belushi / Parminder Nagra / Matisyahu
- 83. James Woods / Piper Perabo / Keaton Simons
- 84. Emma Thompson / Steve Byrne
- 85. Lynn Redgrave / Isaiah Washington / Mutemath
- 86. Mary Steenburgen / Big & Rich
- 87. Jeff Probst / Lauren Holly / Ne-Yo
- 88. Zooey Deschanel / Trace Adkins
- 89. Jean Reno / Sanaa Lathan
- 90. Eddie Izzard / Patti Hall
- 91. Alyson Hannigan / Paul Haggis / Frank Caliendo
- 92. Marlee Matlin / Lisa Loeb
- 93. Paul Reiser / Judy Greer / Jeff Cesario
- 94. Kiefer Sutherland / Amy Adams / Rocco DeLuca and the Burden
- 95. Jason Biggs / Fiona Apple
- 96. William Shatner / Josh Bernstein / Andrea Bocelli
- 97. Carl Reiner / Nadine Velazquez / Robert Hawkins
- 98. Carl Edwards / William H. Macy
- 99. Samuel L. Jackson / Cokie Roberts / The Lashes
- 100. Dolly Parton / Kevin Smith / The Cult
- 101. Terrence Howard / Eric Haney
- 102. Regis Philbin / Tichina Arnold / Jenny Lewis & the Watson Twins
- 103. Roseanne Barr / Wolfgang Puck
- 104. Kathy Bates / Idina Menzel / Jeremy Bloom
- 105. Milla Jovovich / Peter Travers / All American Rejects
- 106. Paul Haggis / Ben Lee / James Blake
- 107. Tyra Banks / Jackie Collins / Nathan Sawaya
- 108. John Larroquette / Ethan Suplee / Fiona Apple
- 109. Wynonna / Emilie de Ravin / D. C. Benny
- 110. David Arquette / Cowboy Troy
- 111. Stockard Channing / Big & Rich
- 112. Rosanne Cash / Howie Mandel
- 113. Jason Lee / Julian Sands / David Gray
- 114. Joan Cusack / Mary McCormack / The New Cars
- 115. Jane Kaczmarek / Tom Fontana / Dan Naturman
- 116. John Goodman / Angela Nissel / Alkaline Trio
- 117. Frankie Muniz / Annie Duke
- 118. Chris Kattan / Mo'Nique / Ozomatli
- 119. Mehcad Brooks / Anjelica Huston / Ne-Yo
- 120. Rosie O'Donnell / Harry Shearer
- 121. Paget Brewster / Sam Elliott / Adam Ferrara
- 122. Ben Kingsley / Roselyn Sánchez / UB40
- 123. Kevin Pollak / Mira Sorvino / Train
- 124. Christian Finnegan / Chi McBride / Bebe Neuwirth
- 125. Carrie Fisher / John Corbett
- 126. Carl Hiaasen / Toby Keith
- 127. Roger Lay Jr. / Ray Romano / Ken Shamrock
- 128. Melina Kanakaredes / Kyle MacLachlan / Shinedown
- 129. Dennis Quaid / The Wiggles
- 130. Radha Mitchell / Marion Ross / Erin Boheme
- 131. Jennifer Finnigan / Barry Sonnenfeld
- 132. Dave Barry / Dem Franchize Boyz
- 133. Kristin Chenoweth / Andy García / Mandy Moore / Rock Bottom Remainders
- 134. Neil Patrick Harris / Parminder Nagra / The BellRays
- 135. Randy Jackson / Connie Schultz
- 136. Reggie Bush / Jennifer Love Hewitt / Frank McCourt / Secret Machines
- 137. Emily Deschanel / Kelsey Grammer / Aisha Tyler / The Go! Team
- 138. Julia Louis-Dreyfus / Ying-Yang Twins
- 139. Denis Leary / Bo Bice
- 140. Donald Faison / Betty White / Bill Bailey
- 141. Bill Carter / Jenna Fischer / Chris Isaak
- 142. Paul Bettany / Kate Walsh / Damian Marley
- 143. Jacinda Barrett / Mark Harmon / Rock Kills Kid
- 144. Daryl Hannah / Sara Ramirez
- 145. Phil McGraw / Jim Gaffigan
- 146. Merv Griffin / Rick Reilly
- 147. Diane Farr / Dominic Monaghan / Phil Vassar
- 148. Mía Maestro / Nick Lachey
- 149. Reba McEntire / Cynthia Watros / Toby Keith
- 150. Anna Paquin / Casper Van Dien / Jason Aldean
- 151. Ricki Lake / Oscar De La Hoya / The Wreckers
- 152. Pauley Perrette / Brooks and Dunn
- 153. Jenny McCarthy / Jim Short / Gomez
- 154. Jon Favreau / Shooter Jennings / Lee Child
- 155. Patricia Heaton / Claire Fordham / The New Cars
- 156. Ian McShane / Joey Lauren Adams / Stanley Bing
- 157. Edie Falco / David Lee Roth
- 158. Tom Everett Scott / Ludacris / Speech
- 159. Sara Rue / Anthony Michael Hall / Secret Machines
- 160. Anderson Cooper / Mercedes Ruehl / Dan Cummins
- 161. Lorraine Bracco / Kevin Connolly / Jamie Jenson
- 162. Tony Shalhoub / Lucy Davis / Echo & the Bunnymen
- 163. Jon Cryer / Jim Short / Three Days Grace
- 164. Pepe the King Prawn / Sarah Wynter / The Charlatans
- 165. Katey Sagal / David Milch / Arturo Gatti
- 166. Stanley Tucci / Cat Deeley / Van Hunt
- 167. Jack Black / James Marsden / Sonya Kitchell
- 168. Tyrese Gibson / Def Leppard / Paul Morrissey
- 169. Regis Philbin / John Landis / Snoop Dogg
- 170. Henry Winkler / Judy Greer / Mike Young
- 171. Dave Foley / Amy Sedaris / UB40
- 172. Tim Robbins / T.I.
- 173. Jesse James / Paul Dinello / She Wants Revenge
- 174. Laurence Fishburne / Illeana Douglas, / Jack's Mannequin
- 175. Tom Lennon / Jewel
- 176. Donal Logue / Ne-Yo
- 177. Toni Collette / Lawrence Block / Joe Theismann
- 178. Julie Chen / Denise Mina / Echo & the Bunnymen
- 179. Danny Bonaduce / Cote De Pablo / Bill McArthur
- 180. Joe Mantegna / Brooks & Dunn
- 181. Nick Cannon / Kyle Dunnigan / Family Force 5
- 182. Eddie Izzard / Greg Warren / The Buzzcocks
- 183. Kevin Smith / Carrie Ann Inaba / Seether
- 184. Cuba Gooding Jr. / Jay Larson / Jurassic 5
- 185. Greg Kinnear / Hugh Hefner / Sammy Hagar
- 186. Kyra Sedgwick / Keith Olbermann
- 187. Andie MacDowell / Cirque du Soleil's KA
- 188. Bonnie Raitt / Travis Pastrana / Randy Kagan
- 189. Drew Pinsky / Carnie Wilson / Tally Hall
- 190. Jaime Pressly / Robbie Coltrane / Michael Franti & Spearhead
- 191. Carlos Mencia / Natasha Bedingfield
- 192. Steve Carell / The Subways
- 193. Aaron Eckhart / Cheyenne Kimball / Fran Solomita
- 194. Tim Olyphant / Lindsay Sloane / The Editors
- 195. Christina Milian / Tim Olyphant / Brian Malow
- 196. Michael Clarke Duncan / Laura Kightlinger / Rob Zombie
- 197. Chi McBride / Lili Taylor / Nick Lachey
- 198. Matt Dillon / Padma Lakshmi / Paula DeAnda / Baby BashMatt Dillon / Padma Lakshmi / Paula DeAnda / Baby Bash
- 199. Alice Cooper / Penelope Ann Miller
- 200. Jane Kaczmarek / Esai Morales / Larke Miller
- 201. Shannen Doherty / Eddie Kaye Thomas / E-40 T-Pain
- 202. Fred Willard / Rachel Blanchard / Stephen J. Cannell
- 203. Amy Smart / Trace Adkins
- 204. Denis Leary / Lewis Dix / Matt Goss
- 205. André Benjamin / David Boreanaz / Mellowdrone